Outthinking and
Outpacing Cancer

A Breakthrough therapeutic intelligence and care model to
battle cancer

Bringing embedded intelligence to the point of care to to deliver precision oncology evidence at the point of care, supporting evidence-informed treatment planning.
This is Precision Oncology 3.0.

A New Operating System for Clinical Outcomes

A Oncology Clinical Outcome Engine enables powered by Multi-Modal data including DNA, RNA, radiology, pathology, EHR data, labs,ctDNA, toxicity and treatment history to deliver optimal therapy options at every step, with clear evidence and explainability.

We built a new operating system for Precision oncology - onethat captures every biological signal, unifies all data streams, and utilizes computational intelligence to drive the best treatment decision for everypatient.

We call this Cancer Clinical Outcome Engine:

As cancer evolves, our system evolves with it, helping oncologists deliver the 

best-matched treatment plan, regardless of location or resource constraints.

New Data
Act
Re-Analysis
Recommend
Refine
Toxicity Alerts
Resistance Maps
Outcome Modeling
Drug Response Predictions
New Data
Act
Re-Analysis
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Recommend

Continuous Cancer Care Intelligence

Our clinical reasoning agents evaluate treatment options,weigh risks and benefits, align with established oncology guidelines, explain therapeutic rationale and automatically re-run analyses whenever new data arrives.

Thisproduces treatment-response insights, resistance signals, toxicity riskfactors, and outcome modeling – not as static reports but asintelligent, operational tools.

Because intelligence only matters at the point of care when it drives outcomes.

Introducing gSage CancerAI

gSage CancerAI is our cancer intelligence and care platform– an integrated system built to provide precision oncology workflow in the clinic. It is the first platform designed to provide precision treatment matching at the point of care.

gSage CancerAI features:

Lightning Mode: Instant Clinical Fact Lookups

Get instant, reliable answers with evidence in seconds for quick reference.

Pro Mode: Deep Research with Reasoning

Synthesize evidence for complex cases and surface clear rationale, with evidence.

Casebook

A live snapshot of the latest patient information powered by gSage Date Flywheel.

Digital Twin

Enables oncologists to simulate the patient’s tumor treatment with every new data update.

One‑Click Tumor Board Presentation Builder

Autogenerate editable briefs with key points and references, with evidence.

One‑Click Treatment Plan Options with Rationale

Context-aware recommendations reflecting prior lines and biomarkers, with evidence.

Built to Learn, Simulate, and Stay Ahead of Cancer

gSage CancerAI learns, updates, and evolves its recommendations, just like the oncologists it supports. It builds a digital twin of each cancer patient to model potential outcomes. It inspires the care team to stay in continual learning mode to outthink and outpace cancer.

We invite you to join the Beta and work together to
outthink and outpace cancer.

Therapeutic Intelligence at the Point of Care

Our GPT-driven platform is embedded in clinical workflow and treatment protocols. We enable real-time decisions around first-line therapy, alternatives for emerging resistance, optimal switch points, next-line strategies after progression, and trial matching based on ongoing biology.

gSage CancerAI will soon include:

Reducing Failed Therapies

Synthesizes evidence from transcriptomics and patient context to prioritize options for clinician review.

Anticipating Resistance Earlier

Flags patterns that may be associated with emerging resistance, prompting consideration of follow-up testing.

Minimizing Toxicities

Checks prior treatments, organ function, and contraindications, to support clinicians by identifying potential risks and outlining evidence-based alternative options.

Improving Treatment Sequencing

Ranks therapies by guideline concordance, biomarker fit, and line-of-care timing.

Supports Clinicians Navigating Complexity

Explainable option summaries with evidence-graded therapeutic option summaries.

1

Reduces Failed Therapies

2

Anticipates Resistance Earlier

3

Minimizes Toxicities

4

Improves Treatment Sequencing

5

Supports Clinicians Navigating Complexity

Precision Oncology maximizes survival opportunities
for every patient – anywhere in the world.

A Companion for Patients and Survivors

Our app empowers people to take better control over their cancer journey.

Understand Your Diagnosis, Clearly

gSage CancerAI chat explains your reports, labs, and scans in plain language.

Be Ready for Every Appointment

Smart question builder creates personalized lists for your provider; save, print, or share securely.

Own Your Data with “My Casebook”

A view that unites reports, biomarkers, treatments, and timelines kept current as new results arrive.

Support Your Mind & Daily Health

CBT-informed chat and mood tracking with simple exercises and weekly insights to help you cope.

Real Time, Biology Tailored Insights

Education and prompts aligned to your data, so you know what to ask, what to watch, and what’s next.

Pioneering Health AI

In a world where healthcare is rapidly evolving, Pioneering Health AI is at the forefront of innovation. GeneSilico™ cutting-edge solutions are designed to empower medical professionals, optimize patient care, and transform the way health data is utilized.

From predictive diagnostics to personalized treatment plans, we harness the power of artificial intelligence to make healthcare smarter, faster, and more efficient.

Multi-Modal Precision Oncology Platform

CancerAI with precision reasoning and actions

A precision oncology platform that dynamically connects genomic interpretation, real-world evidence, and treatment-response evidence and modeling into a single clinical workflow, enabling oncologists to deliver personalized treatment choices at the point of care.

Using biology, chemistry, oncology, and compliance AI agents

A multi-agent clinical orchestration platform that supports point-of-care interpretation, reasoning, and action for oncologists and cancer care teams, with human-in-the-loop control to produce a personalized treatment plan for every patient.

Powered by a vibe computing platform for precision oncology teams

A multi-agent data flywheel that discovers EHR and other data sources, then structures and labels them into enterprise graph ontologies and a context fabric, powering clinical workflows for personalized treatment planning and longitudinal patient tracking.

GeneSilico Oncology LLMs

Join Us in the Fight
Against Cancer

Together, we can reach more patients, improve survival, and transform outcomes. United
as one global team - with technology as our partner - we can advance, learn, and make a
meaningful difference for every person facing cancer.

Drug Efficacy at point of care

Matching a patient's tumor multi-Omics bio-profile with most effective drugs for personalized treatment planning and progress tracking and RWE with Causal explainable AI.

CaseBookLM for Tumor Boards

Matching a patient's tumor multi-Omics bio-profile with most effective drugs for personalized treatment planning and progress tracking and RWE with Causal explainable AI.

Secure and Safe Cancer data Fabric

Source, Generate and Share Case Summaries, Drug Matching Analysis, Tumor Board Briefs and Care Triage powered by Multi-Modal Data.