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gSage TM is an AI-native Precision Oncology Platform.

Our next-generation data and AI infrastructure powers gSage CancerOS.

It turns a patient’s multi-modal information into one AI-ready longitudinal record, simulates therapy response, and learns from every outcome.

gSage Oncology Graphic

Casebook consolidates siloed data into continuous context.
The Digital Twin tests, the oncologist decides, the outcome recalibrates.

Siloed Data to Computed Biology

PATIENT DATA
Screening

Screening

Population risk and early detection

DiagnosticImaging

Diagnostic
Imaging

Multimodal and
quantitative

Biopsy

Biopsy

Tissue sampling and minimally invasive diagnosis

Pathology

Pathology

Morphology,
subtype and
prognostic markers

MolecularCharacterization

Molecular
Characterization

Genomic, transcriptomic
and other biomarkers

Treatment

Treatment

Personalized and
multidisciplinary
care

Outcome

Outcome

Tumor response
and mInimum
residual disease monitoring

Casebook: The Longitudinal System of Record
Multi-modal data computes the biological state of the disease, continuously simulates resistance pathways, and therapy response.
Biological Kernel
GeneSilico creates personalized impact for every patient across the cancer care journey.
See more of the science
Testimonials

“ GeneSilico’s integrated reports provide significantly deeper and more actionable treatment insights compared with interpreting individual diagnostic reports in isolation.

They help me make more informed, personalized, and comprehensive treatment decisions for my cancer patients. “

Dr. P.S. Dattatreya

Dr. P.S. Dattatreya

Chief Medical Oncologist
Clinical Director – Medical Oncology Services
KIMS Hospitals

“ This technology helps us to guide the further treatment so that we can avoid the unnecessary toxicities of medicines, and we can give what medicine is most likely in the given patient.

We have used it.
We are convinced with the results. “

Dr. Amit Upadhyay

Dr. Amit Upadhyay

Hematologist, Oncologist
Senior Consultant
PSRI Hospital

THE PLATFORM

AI-native precision oncology intelligence,
for the clinic and for clinical trials.

Casebook is the longitudinal, multimodal patient record, built at the point of care and reasoned over by specialist agents.

Clinicians

use it for clinical decision support.

Biopharma Developers

use our platform’s de-identified patient data for intelligent cohort selection based on molecular level matching through our gSage Digital Twin simulation.

gSage Platform

One longitudinal patient record. Two products.

gSage Tumor Digital Twin DRIVES POINT OF CARE AND TRIAL DESIGN
FOR CLINICS & HEALTH SYSTEMS

Point-of-care clinical and operational AI

  • Tumor Boards
  • Therapy Simulation
  • Precision Treatment
  • Trial Matching
  • Legal & Compliance
  • Pre-auth and Operations
FOR PHARMA & BIOTECH

Trial design and feasibility intelligence

  • De-identified real-world cohorts drawn from longitudinal records.
  • simulating drug molecules against genetic determinants of response and resistance

Casebook Engine

Current Biological Context of the Patient
EHR Pathology LIS NGS Feeds PACS Imaging Frontier Models
ONCOLOGY RESEARCH AND CLINICAL VALIDATION
gSage Star Icon

+6.5M

longitudinal patient records

feeding the gSage data flywheel for training and validation

HCG Cancer Center
50 patients

in a registered clinical study

HCG Cancer Center

Omega Hospital
500 patients

in a registered clinical study

Omega Hospital

Karkinos
200 patients

in a registered clinical study

Karkinos

THE PATIENT JOURNEY

gSage Connect:
your personalized companion for cancer care

PUBLICATIONS

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against cancer

Live with hundreds of oncologists. Ready for your institution.