Outthinking and
Outpacing Cancer

A New Decision Intelligence and Care Model to Battle Cancer

Bringing embedded intelligence to the point of care to predict drug efficacy and guide personalized treatment choice. This is Precision Oncology 3.0.

A New Operating System for Oncology

A continuous learning model that integrates DNA, RNA, radiology, pathology, EHR data, labs, ctDNA, toxicity and treatment history to compute the optimal therapy at every step.

We built a new operating system for oncology - one that captures every biological signal, unifies all data streams, and utilizes computational intelligence.

We call this integrated biological intelligence:

As cancer evolves, our system evolves with it, helping oncologists deliver the 

best-matched treatment plan, regardless of location or resource constraints.

New Data
Act
Re-Analysis
Recommend
Refine
Toxicity Alerts
Resistance Maps
Outcome Modeling
Drug Response Predictions
New Data
Act
Re-Analysis
Refine
Recommend

Cancer Therapeutic Intelligence

Our clinical reasoning agents evaluate treatment options, weigh risks and benefits, align with established oncology guidelines, explain therapeutic rationale and automatically re-run analyses whenever new data arrives.

This produces drug response predictions, resistance maps, toxicity alerts, and outcome modeling – not as static reports but as intelligent, operational tools.

Because intelligence only matters at the point of care when it drives outcomes.

Introducing gSage CancerAI

gSage CancerAI is our cancer intelligence and care platform – an integrated system built to provide precision oncology workflow in the clinic. It is the first platform designed to provide precision treatment matching at the point of care.

gSage CancerAI features:

Lightning Mode: Instant Clinical Fact Lookups

Get concise, reliable answers in seconds for quick reference, with evidence.

Pro Mode: Deep Research with Reasoning

Synthesize evidence for complex cases and surface clear rationale, with evidence.

Patient Casebooks: Living Digital Twin Workspace

Unite reports, biomarkers, therapies, and notes in one place.

One‑Click Tumor Board Presentation Builder

Autogenerate editable briefs with key points and references, with evidence.

One‑Click Treatment Plan Options with Rationale

Context-aware recommendations reflecting prior lines and biomarkers, with evidence.

Built to Learn, Simulate, and Stay Ahead of Cancer

gSage CancerAI learns, updates, and evolves its recommendations, just like the oncologists it supports. It builds a digital twin of each cancer patient to simulate drug efficacy. It inspires the care team to stay in continual learning mode to outthink and outpace cancer.

We invite you to join the Beta and work together to
outthink and outpace cancer.

Powering Precision Drug Efficacy at Point of Care

Our GPT-driven platform is embedded in clinical workflow and treatment protocols. We enable real-time decisions around first-line therapy, alternatives for emerging resistance, optimal switch points, next-line strategies after progression, and trial matching based on ongoing biology.

gSage CancerAI will soon include:

Reducing Failed Therapies

Predicts likely drug efficacy from transcriptomics and patient history to prioritize responders.

Anticipating Resistance Earlier

Spots early signs of treatment resistance from patterns in test results and past outcomes; prompts timely followup testing.

Minimizing Toxicities

Checks prior treatments, organ function, and contraindications, to suggest safer alternatives with clinical rationale.

Improving Treatment Sequencing

Ranks therapies by guideline concordance, biomarker fit, and lineofcare timing.

Supports Clinicians Navigating Complexity

Explainable recommendations with confidence scores, trial matching, and shareable board ready briefs.

1

Reduces Failed Therapies

2

Anticipates Resistance Earlier

3

Minimizes Toxicities

4

Improves Treatment Sequencing

5

Supports Clinicians Navigating Complexity

Precision Oncology maximizes survival opportunities
for every patient – anywhere in the world.

A Companion for Patients and Survivors

Our app empowers people to take better control over their cancer journey.

Understand Your Diagnosis, Clearly

gSage CancerAI chat explains your reports, labs, and scans in plain language.

Be Ready for Every Appointment

Smart question builder creates personalized lists for your provider; save, print, or share securely.

Own Your Data with “My Casebook”

A view that unites reports, biomarkers, treatments, and timelines kept current as new results arrive.

Support Your Mind & Daily Health

CBT-informed chat and mood tracking with simple exercises and weekly insights to help you cope.

Real Time, Biology Tailored Insights

Education and prompts aligned to your data, so you know what to ask, what to watch, and what’s next.

Pioneering Health AI

In a world where healthcare is rapidly evolving, Pioneering Health AI is at the forefront of innovation. GeneSilico™ cutting-edge solutions are designed to empower medical professionals, optimize patient care, and transform the way health data is utilized.

From predictive diagnostics to personalized treatment plans, we harness the power of artificial intelligence to make healthcare smarter, faster, and more efficient.

Multi-Modal Precision Oncology Platform

CancerAI with precision reasoning and actions

A precision oncology platform that dynamically connects genomic interpretation, real-world evidence, and predicted drug efficacy into a single clinical workflow, enabling oncologists to deliver personalized treatment choices at the point of care.

Using biology, chemistry, oncology, and compliance AI agents

A multi-agent clinical orchestration platform that supports point-of-care interpretation, reasoning, and action for oncologists and cancer care teams, with human-in-the-loop control to produce a personalized treatment plan for every patient.

Powered by a multi-modal oncology data flywheel

A multi-agent data flywheel that discovers EHR and other data sources, then structures and labels them into enterprise graph ontologies and a context fabric, powering clinical workflows for personalized treatment planning and longitudinal patient tracking.

GeneSilico Oncology LLMs

Join Us in the Fight
Against Cancer

Together, we can reach more patients, improve survival, and transform outcomes. United
as one global team - with technology as our partner - we can advance, learn, and make a
meaningful difference for every person facing cancer.

Drug Efficacy at point of care

Matching a patient's tumor multi-Omics bio-profile with most effective drugs for personalized treatment planning and progress tracking and RWE with Causal explainable AI.

CaseBookLM for Tumor Boards

Matching a patient's tumor multi-Omics bio-profile with most effective drugs for personalized treatment planning and progress tracking and RWE with Causal explainable AI.

Secure and Safe Cancer data Fabric

Source, Generate and Share Case Summaries, Drug Matching Analysis, Tumor Board Briefs and Care Triage powered by Multi-Modal Data.