The world’s first cancer Digital Twin Agent designed for the point of care.

CANCER THERAPY SIMULATION BEFORE A SINGLE DOSE

The new superpower for oncologists and hospitals. A molecular replica of each patient’s tumor simulating how it responds, resists, and evolves.

Tests give data. Guidelines give rules. Neither tells you what works for this patient.

0%

FIRST THERAPY FAILURE

Nearly 1 in 3 patients endure an ineffective first therapy.

0%

RESISTANCE-LINKED DEATHS

Most cancer deaths trace back to drug resistance.

0

NEW PAPERS PER YEAR

No oncologist can keep pace with the literature.

0

CANCER TEST TYPES

Each generates data. None tells you what to do with it.

Continuous cancer care intelligence now becomes essential.

Simulate before you treat. Decide with clarity.

The GeneSilico Digital Twin is a continuously updated, patient-specific model of the tumor. Every treatment option is simulated before a decision is made.

CAUSAL PERSONALIZED MULTI-OMICS MULTI-MODAL
Digital Twin

Navigating Cancer Care together.

Oncology AI agents designed for for every step of the Patient journey

Casebook

Casebook

AI-native clinical EHR. Six specialized agents. Any test ingested.

MyCasebook

MyCasebook

The patient’s AI co-pilot. Genomic data in plain language.

Digital Twin

Digital Twin

Molecular cancer therapy simulation. Every treatment ranked.

Deep Precision NGS

Deep Precision NGS™

Cancer sequencing panels, built for the Digital Twin.

Clinical Orchestration and Control Plane

One secure, governed platform.

The gSageTM Platform The most trustworthy cancer AI is the one that can prove, explain and govern every decision.

One secure, governed platform beneath every point of care.

EXPLORE PLATFORM

gSage helps anticipate challenges and navigate decisions

Simulate response before the first dose, not after three, sparing patients the burden of cycling through options that won't work.

Molecular changes caught weeks before imaging confirms failure.

Pharmacogenomic flags surface risk before it reaches the patient.

Next-line options modeled now, ready the moment they're needed.

GAP tags surface what to order before it’s needed, UG- T1A1 before sacituzumab, HbA1c before alpelisib, ranked.

Therapies Ranked by Digital Twin Simulation

Patient #4471

Regimen A
0%
Regimen B
0%
Regimen C
0%

● Resistance model flagged and deprioritized

Accelerated Drug Validation ››› RTCT-Aligned

From molecule to proven patient efficacy.

GeneSilico closes the gap between AI drug discovery and human proof, generating efficacy evidence continuously across an oncology hospital and CRO network for AI-native biotech and pharma.

Start

Molecule

An AI-discovered candidate, ready for human proof.

Model

Digital Twin

Response modeled patient by patient, before a dose.

Run

Real-time trial

Multicentre study across the hospital and CRO network.

Prove

Proven efficacy

Structured, auditable evidence to sponsors and regulators.

ARTICLES
Nature Communications • Sep 2022

Gene expression based inference of cancer drug sensitivity

Predictive modeling approach to infer treatment response in cancers.

NPJ Systems Biology and Applications • Jun 2026

Optimizing genomics-aware clinical agents in precision oncology

Prestigious international research grant recognizing GeneSilico's contribution to AI-guided oncology therapy and drug resistance modelling.

Join us in the fight
against cancer

Live with hundreds of oncologist. Ready for your institution.

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